Interventional Cardiology and Angiology

• Randomized Evaluation of Equivalence of conservative versus interventional strategy in patients with unstable angina pectoris or non-Q-wave infarction (SPREE) study investigators
• Recent clinical trials have questioned the value of early invasive diagnosis and early interventional strategy in patients with unstable angina pectoris. They have rather favoured a conservative approach.
• Hypothesis:
  • Optimal interventional strategy combined with an appropriate adjunctive therapy will improve the outcome in patients with unstable angina pectoris as compared to conservative strategy. In addition, an optimal conservative approach with a long lasting period of plaque passivation will significantly decrease morbidity and mortality in these patients as compared to standard therapy.