27.-28. November 1998, Berlin, Germany
 
 

Registration information

Completed registration forms must be mailed to the Congress Office

Congress fee: 200 DM

The registration fee includes admission to all sessions, coffee, tea, lunches Full payment by cheque or by bank transfer must accompany your registration.

Please transfer to

Robert-Rössle-Klinik

Account No. 20 5000 5515

�Sentinel Node Congress 9542639�

Berliner Sparkasse

Bank Code 100 50000

Congress Secretaries

Dr. A. Bembenek

Dr. B. Lustig

Congress Office

M. Henschel

Klinik für Chirurgie und Chirurgische Onkologie

Universitätsklinikum Charité der HUB

Robert-Rössle-Klinik

13125 Berlin

Tel. +49-30-9417 1403

Fax +49-30-9417 1404

e-mail [email protected]

Language

The official congress language will be English.

Congress Venue

Hilton Berlin Hotel

Mohrenstrasse 30

10117 Berlin

Tel. +49-30-2023-0

Fax +49-30-2023-4269

Hotel Reservation:

Hilton Berlin Hotel

Special rate, please refer to

�Metastases Congress�

If you are interested in alternative overnight accomodation, please contact

Berlin Association Bureau

10785 Berlin, Am Karlsbad 11

Tel. +49-30-2500 25

Fax +49-30-2500 2424

Metastases determine malignancy. The general attention so far was focused upon organ metastases. The molecular mechanisms thereof, while far from beeing totally elucidated, are increasingly well understood. Modern diagnostic tools now enable detection and precise localization of small lesions. In contrast, our knowledge and diagnostic capabilities regarding metastatic spread to the lymphatic system is rather limited. However, there is a number of interesting recent advances and developments. It is the aim of this conference to submit these findings to detailed analysis and discussion and to provide an outlook on future prospects.

The therapeutic relevance of an enhanced sensitivity in lymph node metastases detection has to be considered with regard to increased morbidity versus eventual prognostic improvements by adjusted therapy.An interesting concept which might improve the diagnostic accuracy while reducing operative morbidity is the �sentinel node � technique. However, surgical standards lack and many fundamental questions regarding to precise lymphatic mapping remain unanswered. Whether the concept is of general relevance or whether efficacy and applicability are limited to a very few organ sites is still undetermined. The symposium shall provide intensive discussion of these questions under methodological and tumour biological aspects. World-renowned experts with a long-time involvement in related basic and clinical research will provide us with a broad survey of actual knowledge together with a critical appraisal of actual and future developments.

I cordially invite you to Berlin, to participate in this exceptional meeting about a clinically and biologically highly actual and relevant topic. I would enjoy if you would personally contribute to a stimulating and fruitful discussion and workshop.

Peter M. Schlag

Professor of Surgery

Chairman
 
 
 
 
 PROGRAM

Friday, 27. Nov. 1998

8.00-10.00 Session I
 
 

Imaging of lymph node metastases

Chairmen: R. Felix / D. L. Munz

New developments in MR-lymph node imaging

B. Hamm, Berlin, Germany

Efficacy of immunoscintigraphy for the detection of lymph node metastases

K. E. Britton, London, U.K.

Sensivity and specifity of PET for the diagnosis of lymph node metastases

M. Strauss, Heidelberg, Germany

10.00-11.15 Session II

Assessment of lymph node metastases

Chairmen: H. E. Gabbert / K. W. Jauch

Diagnosis and staging of lymph node metastases

Ch. Wittekind, Leipzig, Germany

Detection and relevance of immunohistochemi-cally identifiable tumor cells in lymph nodes

K. Pantel, München, Germany

Molecular diagnosis of lymph node metastases

R. H. Brakenhoff, Amsterdam, The Netherlands

11.15-11.30 Coffee break

11.30-13.00 Session III

Basics of lymphatic metastasis

Chairmen: W. Birchmeier / M. Lipp

Cell biology of lymphatic metastases

S. Eccles, London, UK

Molecular and cellular mechanisms in lymph node metastasis

J. Sleeman, Karlsruhe

Functional anatomy of lymphatic vessels under the aspect of tumor invasion

J. A. Werner, Marburg, Germany

13.00-14.00 Lunch

14.00-15.15 Session IV
 
 

Principles of lymphatic mapping and SN detection

Chairmen: W. H. Knapp / P. Hohenberger

The concept of the sentinel node

R. M. Cabanas, New York, USA

Particle size, lymphoscintigraphy and the SN concept

G. Paganelli, Milan, Italy

Vital dye and radiolabeled colloids � complement or alternative

R. Pijpers, Amsterdam, The Netherlands

15.15-15.30 Coffee break

15.30-16.30 Session V

SN detection in urogenital cancer

Chairmen: W. Lichtenegger / S. A. Loening

Application of the SN concept in urogenital cancer

R. M. Cabanas, New York, USA

Lymphatic mapping in vulvar and endometrial cancer

C. Levenback, Houston, USA

16.30-18.00 Session VI

SN Detection in malignant melanoma

Chairmen: E. Bröcker / N. Senninger

Development and clinical application of the SN concept for melanoma patients

M. Ross, Houston, USA

Perspectives of the SN concept for melanoma patients

A.M.M. Eggermont, Rotterdam, Netherlands

20.00 Social event

 
8.00-9.00 Session VII

SN detection in neck and thyroid cancer

Chairmen: H. J. Buhr / H. D. Röher

Selective neck dissection based on SN biopsy

G. Mamelle, Villejuif, France

Recent results of SN lymphadenectomy in thyroid malignancies

A. E. Giuliano, Santa Monica, USA

SN Detection in combination with echo-guided aspiration biopsy

M. v. d. Brekel, Amsterdam, Netherlands

9.00-11.30 Session VIII

SN detection in breast cancer

Chairmen: H. Graeff / G. Bastert

Present and future of SN lymphadenectomy in breast cancer

U. Veronesi, Milan, Italy

Potential and pitfalls of SN detection in breast cancer

A.E. Giuliano, Santa Monica, USA

Sentinel node and bone marrow micrometastases in breast cancer

P. M. Schlag, Berlin, Germany

Therapeutic significance of sentinel lymph nodes in breast cancer

H.J. Senn, St. Gallen, Switzerland

11.30-12.00 Coffee break

12.00-13.00 Session IX

SN detection in gastric cancer

Chairmen: J. R. Siewert / J. M. Müller

Lymph node dissection for gastric cancer guided by India ink staining

T. Sano, Tokyo, Japan

Potential and futility of SN detection for gastric cancer

C.J. H. van de Velde, Leiden, The Netherlands

13.00-14.00 Session X

SN detection in colorectal cancer

Chairmen: Ch. Herfarth / H. P. Bruch

Probe guided surgery in colorectal cancer

P. Lechner, Klosterneuburg, Austria

Identification of lymph node metastases in recurrent colorectal cancer

S. Schneebaum, Tel Aviv, Israel

Autofluorescence to detect lymph node metastases in colorectal cancer

K. T. Moesta, Berlin, Germany

Lunch and Adjourn